What do you mean by audio conference? Is this a bunch of people on a telephone line? What do you mean by web conference? Do you mean a chat room (text only)? Do you expect users to talk into microphones, and have their voice transmitted over the net? Do your clients want video? For everyone? Does one party do all the talking, and everyone else does all the listening (and/or watching)?
This problem isn't by any means simple to solve. As you can see, there's a lot of questions that you need to answer. I suspect that it'd be cheaper to use off-the-shelf conferencing software / hardware (web cams, microphones, etc) than it would be to pay someone to write this application from scratch.
Take care,
Nik
http://www.bigaction.org/