You could do that, esp. if the ".mdb" file isn't too large.
If it's a large file, you should go find an FTP component that you could script from ASP and use that. Would be much more efficient than trying to use MSXML2.ServerXMLHTTP (which is what you would use if you don't use FTP).
On the side that is "sending" the ".mdb" file, you'd use an ADODB.Stream object and check for a username/password sent as part of the request from the receiving machine. (You surely wouldn't want to just allow direct download of the file, as then some hacker could discover it and grab it.)
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