Is there any method to change the globalization dynamically with the control of other dotnet pages?

I would like to build a web page with mutiple language by changing the skin of the web pages.

However, how to assign the following back to the web.config?
<globalization fileEncoding="" requestEncoding="" responseEncoding="" culture="" uiCulture="" />

My first idea is assign some variables into the web.config and change the variable by the skind later, but how?

Hope somebody can help me to solve this question, thanks.

|:|KUNG|:|

You can handle the globalization variable like this
Thread.CurrentThread.CurrentUICulture = new CultureInfo("de-DE");