May i know how to scripting (WSH or any web method) method to add new URL into (Truested Sites) Zone in [Tool -> Internet Options -> Security] in Internet Explorer.

Or do anybody know how to edit values in Registry related to this
Trusted Sites Zone (2)?

Actually i need to set only my app URL for client that access my web app.

See this article: http://support.microsoft.com/default.aspx?kbid=182569

mmcdonal

If your app URL is NOT in a zone that allows scripting access to the system, you won't be able to make this change.

Example:
mysite.com <- is in the restricted zone
the browser does not allow scripting to make these kind of changes so it won't be able to add itself to the Trusted zone.

This is a security feature. If a site could do this then the whole zone thing would be useless as a hacker's script would be able to add itself to a trusted zone, which would increase it's security access to the browser, and work from there.

If you figure out a way around this, please let me know. I'd be curious to see how it's done.