I am trying to put two dropdown lists on a page just by using ASP.Net(VB) How can I accomplish this so that the content of the second dropdown list is controlled by the first? ideally I'd like to populate the first and second one using a web control attached to an Access db; when the SelectedIndexChanged event fires, I'd like the select command that the second web control (for the second dropdown list) to be changed based upon the first selection (so that the second list's contents change upon changing the contents of the first).

Will the 2nd ddl have anything at the start?

In your event handler once you have the change for ddl then call a sub that populates the 2nd ddl based on the selected item.

The second ddl will have nothing at start. I am using ASP.NET WebMatrix. Should that cause problems if I am trying to accomplish this?

So basically I have the SelectedIndexChanged event for the first list call a second sub which then does the DataBind() for the second DropDown list? Where should I attempt to define the Select Command for the second web control (before it does a DataBind()?) Thanks a lot.

You can even allow the SelectedIndexChanged Event bind the 2nd ddl. You would bind it just like the 1st ddl and make the necessary modifications based off the 1st ddl's selected value.